Histotripsy Group
    Biomedical Engineering Department, University of Michigan




During Treatment

After Treatment



Research -> Histotripsy Imaging Feedback

Histotripsy Imaging Feedback





During Treatment


A dynamically changing hyperechoic (bright) zone in B-mode ultrasound imaging is an indicator that the histotripsy process is progressing normally. This hyperechoic zone is the sound

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After Treatment


Significant reduction in speckle amplitude within the treated region is observed in B-mode ultrasound imaging after the histotripsy treatment.


Sample B-scan images before and after treatment and corresponding histograms for the treatment area ROI indicated by the square. B-scan images are displayed on a 60 dB dynamic range scale. The significant echogenicity change is caused by a shift in the backscatter amplitude distribution.

References:
Hall TL, Fowlkes JB, Cain CA, "Imaging feedback of tissue liquefication (Histotripsy) in ultrasound surgery," Proc. international 2005 IEEE Ultrasonics Symposium 3, 1732-1734 (2005).

Hall TL, Fowlkes JB, Cain CA, "A real-time measure of cavitation unduced tissue disruption by ultrasound imaging backscatter reduction," IEEE Trans. Ultrason. Ferroelectr. Freq. Control 54, 569-575 (2007).