Conference Proceedings (Before 2014)

Conference Proceedings

2013

A. P. Duryea, C. A. Cain, W. W. Roberts, H. A. Tamaddoni, T. L. Hall, “Active removal of a residual bubble nuclei following a cavitation event,” Proc. IEEE Ultrasonics Symposium, pp. 1813-1816, 2013. 

Y. Kim, E. Vlaisavljevich, G. Owens, S. Allen, C. A. Cain, and Z. Xu, “In Vivo Transcostal Histotripsy Therapy without Aberration Correction,” Proc. IEEE Ultrasonics Symposium, pp. 1817-1820, 2013. 

R. M. Miller, X. Chang, A. D. Maxwelll, T.-Y. Wang, J. B. Fowlkes, C. A. Cain, and Z. Xu, “Investigation of the mechanism of ARFI-based color Doppler feedback of histotripsy tissue fractionation,” Proc. IEEE Ultrasonics Symposium, pp. 934-937, 2013. 

E. Vlaisavljevich, Y. Y. Durmaz, A. Maxwell, M. El-Sayed, and Z. Xu, “Nanodroplet-Mediated Histotripsy Ultrasound Therapy for Targeted Cancer Ablation,” presented in 2013 IEEE International Ultrasonics Symposium, Prague, Czech Republic, July 21-25, 2013. 

2012

A. P. Duryea, W. W. Roberts, C. A. Cain, and T. L. Hall, “Optically Triggered Solid State Driver for Shock Wave Therapy,” 11th International Symposium on Therapeutic Ultrasound, pp. 76-80, 2012. 

A. P. Duryea, W. W. Roberts, C. A. Cain, and T. L. Hall, “Controlled Cavitation to Augment SWL Stone Subdivision: Mechanistic Insights In-Vivo,” Proc. IEEE Ultrasonics Symposium, pp. 2603-2606, 2012. 

K.-W. Lin, T.-Y. Wang, T. L. Hall, C. A. Cain, D. A. Merton, F. Forsberg, B. B. Goldberg, and J. B. Fowlkes, “Noninvasive Approach for Metastatic Lymph Node Ablation using Histotripsy Tissue Fractionation,” Proc. IEEE International Ultrasonics Symposium, pp. 1007-1010, 2012. 

R. M. Miller, A. D. Maxwell, T.-Y. Wang, J. B. Fowlkes, C. A. Cain, and Z. Xu, “Real-time elastography-based monitoring of histotripsy tissue fractionation using color doppler,” Proc. IEEE Ultrasonics Symposium, pp. 196-199, 2012. 

E. Vlaisavljevich, Y. Kim, S. Allen, G. Owens, S. Pelletier, K. Ives, and Z. Xu, “Image-Guided Non-Invasive Ultrasound Liver Ablation using Histotripsy: Feasibility Study in an in vivo Porcine Model,” presented in 2012 IEEE International Ultrasonics Symposium, Dresden, Germany, October 7-10, 2012. 

2011

Y. Kim, C. Fifer, S. Gelehrter, G. Owens, E. Vlaisavljevich, C. Cain, and Z. Xu, “Non-invasive fetal therapy using histotripsy: safety and local impact on fetal development,” Proc. IEEE Ultrasonics Symposium, pp. 1874-1877, 2011. 

K.-W. Lin, T.-Y. Wang, R. E. Kumon, C. X. Deng, Z. Xu, T. L. Hall, J. B. Fowlkes, and C. A. Cain, “Ultrasound Backscatter Spectrail Analysis Provides Image Feedback for Histotripsy Tissue Fracntionation,” Proc. IEEE International Ultrasonics Symposium, pp. 33-36, 2011. 

A. D. Maxwell, S. Park, C. A. Cain, and Z. Xu, “Trapping of solid particles by cavitation-induced acoustic streaming,” Proc. IEEE Ultrasonics Symposium, pp. 1506-1509, 2011. 

R. M. Miller, Y. Kim, K.-W. Lin, G. Owens, C. A. Cain, and Z. Xu, “Real-time motion tracking for non-invasive ultrasound cardiac therapy using histotripsy,” presented in Proc. IEEE Ultrasonics Symposium, pp. 935-938, 2011. 

S. Park, A. D. Maxwell, G. Owens, H. S. Gurm, C. A. Cain, and Z. Xu, “The effect of acoustic parameters on the non-invasive embolus trap (NET) using a histotripsy-generated bubble cloud,” Proc. IEEE Ultrasonics Symposium, pp. 1878-1881, 2011. 

A. P. Duryea, W. W. Roberts, C. A. Cain, and T. L. Hall, “Optically Triggered Solid State Driver for Shock Wave Therapy,” presented in 2011 IEEE International Ultrasonics Symposium, Orlando, FL, October 18-21, 2011. 

E. Vlaisavljevich, C. A. Cain, and Z. Xu, “Effect of Histotripsy on Tissues with Different Mechanical Properties,” presented in 2011 IEEE International Ultrasonics Symposium, Orlando, FL, October 18-21, 2011. 2011. 

T.-Y. Wang, T. L. Hall, Z. Xu, J. B. Fowlkes, and C. A. Cain, “Image feedback of histotripsy treatments using ultrasound transient elastography,” Proc. IEEE Ultrasonics Symposium, pp. 2233-2236, 2011. 

2010

A. P. Duryea, W. W. Roberts, C. A. Cain, and T. L. Hall, “Optimization of Histotripsy for Kidney Stone Erosion,” presented in 2010 IEEE Ultrasonics Symposium, 5A-5, San Diego, CA, Oct. 11-14, 2010. 

Y. Kim, T.-Y. Wang, Z. Xu, and C. A. Cain, “Lesion Generation through Ribs without Aberration Correction using Cavitational Therapy,” presented in 2010 IEEE Ultrasonics Symposium, 5A-6, San Diego, CA, Oct. 11-14, 2010. 

K.-W. Lin, X. Shao, Z. Xu, J. B. Fowlkes, and C. A. Cain, “Ultrasound-Induced Fluid Uptake Phenomenon in Porcine Uterine Tissue,” presented in 2010 IEEE Ultrasonics Symposium, 5A-4, San Diego, CA, Oct. 11-14, 2010. 

R. M. Miller, G. Owens, G. Ensing, A. Ludomirsky, C. A. Cain, Z. Xu, “Histotripsy for Pediatric Cardiac Applications: In Vivo Neonatal Pig Model,” 9th International Symposium on Therapeutic Ultrasound, pp 15-18, 2010. 

A. D. Maxwell, C. A. Cain, J. B. Fowlkes, and Z. Xu, “Inception of Cavitation Clouds by Scattered Shockwaves,” presented in 2010 IEEE Ultrasonics Symposium, , 3B-2, San Diego, CA, Oct. 11-14, 2010. 

A. D. Maxwell, T.-Y. Wang, L. Yuan, A. Duryea, Z. Xu, and C. A. Cain, “A Tissue Phantom for Evaluation of Mechanical Damage Caused by Cavitation,” 9th International Symposium on Therapeutic Ultrasound, pp 31-35, 2010. 

T.-Y. Wang, T. L. Hall, Z. Xu, J B. Fowlkes, and C. A. Cain, “Local cavitation suppression using cavitation nuclei preconditioning for precise treatment in histotripsy,” presented in 2010 IEEE Ultrasonics Symposium, 5A-3, San Diego, CA, Oct. 11-14, 2010. 

T.-Y. Wang, A. D. Maxwell, S. P., Z. Xu, J. B. Fowlkes, and C. A. Cain, “Why Are Short Pulses More Efficient in Tissue Erosion Using Pulsed Cavitational Ultrasound Therapy (Histotripsy)?,” 9th International Symposium on Therapeutic Ultrasound, pp 40-43, 2010. 

2009

A. Duryea, A. D. Maxwell, W. Roberts, Z. Xu, T. L. Hall, and C. A. Cain, “Non-invasive Comminution of Renal Calculi Using Pulsed Cavitational Ultrasound Therapy – Histotripsy,” Proc. IEEE Ultrasonics Symposium, pp.73-76, 2009. 

Y. Kim, C. G. Fifer, S. K. Gelehrter, J. Williams, J. C. Lu, C. A. Cain, and Z. Xu, “Non-invasive Fetal Therapy using Histotripsy: Feasibility Study in the Sheep Model” Proc. IEEE Ultrasonics Symposium,pp. 228-231, 2009. 

A. D. Maxwell, G. Owens, H. S. Gurm, C. A. Cain, and Z. Xu, “In-Vivo Study of Non-Invasive Thrombolysis by Histotripsy in a Porcine Model,” Proc. IEEE Ultrasonics Symposium, pp. 220-223, 2009. 

A. D. Maxwell, T.-Y. Wang, C. A. Cain, J. B. Fowlkes, O. A. Sapozhnikov, M. R. Bailey, and Z. Xu, “The Role of Compressional Pressure in the Formation of Dense Bubble Clouds in Histotripsy,” Proc. IEEE Ultrasonics Symposium, pp. 81-84, 2008. 

A. D. Maxwell, T.-Y. Wang, L. Yuan, A. Duryea, Z. Xu, and C. A. Cain, “A Tissue Phantom for Evaluation of Mechanical Damage Caused by Cavitation,” 9th International Symposium on Therapeutic Ultrasound, pp 31-35, 2009. 

R. M. Miller, G. Owens, G. Ensing, A. Ludomirsky, C. A. Cain, Z. Xu, “Histotripsy for Pediatric Cardiac Applications: In Vivo Neonatal Pig Model,” 9th International Symposium on Therapeutic Ultrasound, pp 15-18, 2009. 

W. W. Roberts, A. M. Lake, T. L. Hall, J. B. Fowlkes, and C. A. Cain, “Histotripsy of the prostate in a canine model: Non-invasive non-thermal tissue debulking,” 7th International Symposium on Therapeutic Ultrasound, 2008. (In Press) 

T.-Y. Wang, A. D. Maxwell, S. P., Z. Xu, J. B. Fowlkes, and C. A. Cain, “Why Are Short Pulses More Efficient in Tissue Erosion Using Pulsed Cavitational Ultrasound Therapy (Histotripsy)?,” 9th International Symposium on Therapeutic Ultrasound, pp 40-43, 2009. 

T.-Y. Wang, Z. Xu, T. L. Hall, J B. Fowlkes, W. W. Roberts, and C. A. Cain, “Active Protection in Pulse Cavitational Ultrasound Therapy (Histotripsy),” Proc. IEEE Ultrasonics Symposium, pp. 212-215, 2009. 

2008

T. L. Hall, C. R. Hempel, A. M. Lake, K. Kieran, K. Ives, J. B. Fowlkes, C. A. Cain, and W. W. Roberts, “Histotripsy for the treatment of BPH: evaluation in a chronic canine model,” Proc. IEEE Ultrasonics Symposium, pp.765-767, 2008. 

A. D. Maxwell, C. A. Cain, H. S. Gurm, J. B. Fowlkes, and Z. Xu., “Non-Invasive Thrombolysis Induced by Histotripsy Pulsed Cavitation Ultrasound Therapy,” Proc. IEEE Ultrasonics Symposium, pp.1167-1170, 2008. 

W. W. Roberts, A. M. Lake, T. L. Hall, J. B. Fowlkes, and C. A. Cain, “Histotripsy of the prostate in a canine model: Non-invasive non-thermal tissue debulking,” 7th International Symposium on Therapeutic Ultrasound, 2008. (In Press) 

T.-Y. Wang, Z. Xu, F. Winterroth, T. L. Hall1, J B. Fowlkes, E. D. Rothman, W. W. Roberts, and C A. Cain, “Quantitative Image Feedback for Pulsed Cavitational Ultrasound Therapy- Histotripsy,” Proc. IEEE Ultrasonics Symposium , pp. 867-870, 2008. 

2007

J. B. Fowlkes, “Applications of Bubbles in Ultrasonic Therapy,” presented at International symposium on therapeutic ultrasound, OS05_1, Seoul, Korea, Jun 12-15 2007. 

T. L. Hall, K. Kieran, J. B. Fowlkes, C. A. Cain, and W. W. Roberts, “Temporal trends in the histology of the rabbit kidney after cavitational tissue ablation,” 6th International Symposium on Therapeutic Ultrasound, pp. 191-197, 2007. 

T. L. Hall, G. R. Lee, L. Hernandez, and C. A. Cain, “Relaxation Properties of Cavitation Induced Tissue Lesions,” Poster at Joint Annual Meeting ISMRM (International Society for Magnetic Resonance in Medcine)-ESMRMB (European Society for Magnetic Resonance in Medicine and Biology), pp. 1118, May 19-25 2007. 

K. Kieran, T. L. Hall, J. E. Parsons, J. S. Wolf Jr., J. B. Fowlkes, C. A. Cain, and W. W. Roberts, “Exploring the acoustic parameter space in ultrasound therapy: Defining the threshold for cavitational effects,” 6th International Symposium on Therapeutic Ultrasound, pp. 185-190, 2007. 

A. Lake et al, “Cavitational Ultrasound: A Potential Minimally Invasive Therapy for BPH,” Poster at American Urological Association annual meeting, Anaheim, CA, May 23, 2007. 

A. Lake et al, “Histotripsy Threshold of Various Renal Tissues in Porcine Kidney,” Poster at Engineering and Urology Society submeeting at the American Urological Association annual meeting, Anaheim, CA, May 19, 2007. 

W. W. Roberts, A. M. Lake, T. L. Hall, J. B. Fowlkes, and C. A. Cain, “Histotripsy of the prostate in a canine model: non-invasive non-thermal tissue debulking,” Presented at International symposium on therapeutic ultrasound, OS05_4, Seoul, Korea, Jun 12-15 2007. 

F. Winterroth, Z. Xu, T.-Y. Wang, W. W. Roberts, J. B. Fowlkes, and C. A. Cain, “Tissue Fragmentation Treatment by Pulsed Cavitational Ultrasound Therapy-Histotripsy,” presented at 13th International Symposium on Applied Electromagnetics and Mechanics (ISEM), East Lansing, MI, USA, 9-12 Sep 2007. 

Z. Xu, M. Raghavan, T. L. Hall, M.-A. Mycek, J. B. Fowlkes, and C. A. Cain, “Evolution of bubble clouds produced in pulsed cavitational ultrasound therapy – histotripsy,” Poster at International symposium on therapeutic ultrasound, pp. PS02_1, Seuol, Korea, Jun 12-15 2007. 

2006

C. A. Cain, “Histotripsy: controlled mechanical sub-division of soft tissues by high intensity pulsed ultrasound,” Invited talk IEEE International Ultrasonics Symposium, 1D-1, 2006. 

K. Kieran, T. L. Hall, J. E. Parsons, J. S. Wolf, J. B. Fowlkes, C. A. Cain, and W. W. Roberts, “Exploring the Acoustic Parameter Space in Ultrasound Therapy: Defining the Threshold for Cavitational Effects,” 6th International Symposium on Therapeutic Ultrasound, pp. S01, 2006. 

T. L. Hall, K. Kieran, J. B. Fowlkes, C. A. Cain, and W. W. Roberts, “Temporal trends in the histology of the rabbit kidney after cavitational tissue ablation,” 6th International Symposium on Therapeutic Ultrasound, pp. S07, 2006. 

Z. Xu, T. L. Hall, J. B. Fowlkes, and C. A. Cain, “Size measurement of tissue debris generated from mechanical tissue fractionation by cavitational pulsed ultrasound therapy – histotripsy,” 6th International Symposium on Therapeutic Ultrasound, pp. O60, 2006. 

Z. Xu, M. Raghavan, T. L. Hall, C.-W. Chang, M.-A. Mycek, J. B. Fowlkes, and C. A. Cain, “High Speed Imaging of Bubble Cloud in Pulsed Cavitational Ultrasound Therapy – Histotripsy,” Proc. IEEE International Ultrasonics Symposium, pp. 1D-4, 2006.

2005

C. A. Cain, “Histotripsy: controlled mechanical sub-division of soft tissues by high intensity pulsed ultrasound,” International symposium on therapeutic ultrasound, pp. T005, 2005. 

J. B. Fowlkes, O. D. Kripfgans, and A. M. Lo, “Production and use of microbubbles in therapeutic ultrasound,” International symposium on therapeutic ultrasound, pp. T006, 2005. 

T. J. Hall and C. A. Cain, “A Low cost, compact, 512 channel therapeutic system for transcutaneous ultrasound surgery,” International symposium on therapeutic ultrasound, pp. S035, 2005. 

J. E. Parsons, J. B. Fowlkes, and C. A. Cain, “Acoustic backscatter features associated with production of tissue homogenate using pulsed cavitational ultrasound therapy,” International symposium on therapeutic ultrasound, pp. S024, 2005. 

Z. Xu, J. B. Fowlkes, and C. A. Cain, “Optical and acoustic monitoring of bubble dynamics at a tissue-fluid interface in ultrasound tissue erosion,” International symposium on therapeutic ultrasound, pp. S03, 2005. 

2004

M. Cooper, Z. Xu, E. D. Rothman, A. M. Levin, A. P. Advincula, J. B. Fowlkes, and C. A. Cain, “Controlled Ultrasound Tissue Erosion: the Effects of Tissue Type, Exposure Parameters and the Role of Dynamic Microbubble Activity,” Proc. 2004 IEEE International Ultrasonics, Ferroelectric, and Frequency Control Joint 50th Anniversary Conference, vol. 3, pp. 1808-11, 2004. 

J. E. Parsons, C. A. Cain, and J. B. Fowlkes, “Characterizing pulsed ultrasound therapy for the production of cavitational lesions,” Proc. 4th Int. Symp. Therapeutic Ultrasound, AIP conf. Proc. 754, pp. 178-180, 2004. 

B. C. Tran, J. B. Fowlkes, and C. Cain, “Correlation between acoustic backscatter variability and tissue damage prodcued by pulses cavitational ultrasound therapy,” Proc. 2004 IEEE International Ultrasonics, Ferroelectric, and Frequency Control Joint 50th Anniversary Conference, vol. 2, pp. 1461-4, 2004. 

2003

B. C. Tran, J. Seo, T. L. Hall, Z. Xu, K. Ives, J. B. Fowlkes, and C. A. Cain, “In vivo Comparison of Multiple Pulse and CW strategies for Microbubble-Enhanced Ultrasound Therapy.,” Proc. IEEE Ultrasonics Symposium, pp. 909-912, 2003. 

Z. Xu, A. Ludomirsky, L. Y. Eun, T. L. Hall, B. C. Tran, J. B. Fowlkes, and C. A. Cain, “Cavitional Tissue Erosion by Therapeutic Ultrasound,” Proc. Modelling and Experimental Measurements in Acoustics III, pp. 411-421, 2003. 

Z. Xu, A. Ludomirsky, L. Y. Eun, T. L. Hall, B. C. Tran, J. B. Fowlkes, and C. A. Cain, “Controlled Ultrasound Tissue Erosion,” Proc. 2003 IEEE Ultrasonics Symposium, pp. 732-735, 2003. 

2000 – 2002

J. Seo, B. C. Tran, T. L. Hall, J. B. Fowlkes, M. O’Donnell, and C. A. Cain, “Evaluation of tissue damage based on changes in echogenicity,” Proc. 2002 IEEE Ultrasonics Symposium, vol. 2, pp. 1431-4, 2002. 

B. C. Tran, J. Seo, J. B. Fowlkes, and C. A. Cain, “The effect of microbubble concentration on thresholds for tissue damage produced by single bursts of high intensity ultrasound during continuous optison infusion,” Proc. 2002 IEEE Ultrasonics Symposium, vol. 2, pp. 1411-1414, 2002. 

B. C. Tran, J. Seo, J. B. Fowlkes, and C. A. Cain, “Microbubble enhanced threshold reductions for tissue damage using high Intensity ultrasound,” Proc. IEEE Ultrasonics Symposium, vol. 2, pp. 1389-1392, 2001. 

B. C. Tran, T. L. Hall, J. B. Fowlkes, and C. A. Cain, “Noninvasive ultrasound surgery: role of microbubble enhanced cavitation,” Proc. 2000 IEEE Ultrasonics Symposium, vol. 2, pp. 1425-1428, 2000.