Journal Publications (2015 ~ Present)

2019

Li Y, Hall TL, Xu Z and Cain CA. Enhanced Shock Scattering Histotripsy With Pseudomonopolar Ultrasound Pulses. IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, vol. 66, no. 7, pp. 1185-1197, July 2019. 

Gerhardson T, Sukovich JR, Lundt J, Lu N, Pandey A, Cain CA, Xu Z, Hall TL. Design of a Histotripsy Array for the Treatment of Intracerebral Hemorrage. The Journal of the Acoustical Society of America 145, 1862 (2019)

Gerhardson T, Sukovich JR, Chaudhary N, Chenevert TL, Ives K, Hall TL, Camelo-Piragua S, Xu Z, Pandey A, Histotripsy Clot Liquefaction in a Porcine Intracerebral Hemorrhage Model, Neurosurgery, nyz089

Wilson CT, Hall TL, Johnsen E, Mancia L, Rodriguez M, Lundt JE, Colonius T, Henann DL, Franck C, Xu Z, Sukovich JR “Comparative study of the dynamics of laser and acoustically generated bubbles in viscoelastic media“. Physical Review E. 04/2019; 99(4): 043103

2018

Shi A, Lundt JE, Deng Z, Macoskey JJ, Gurm H, Owens G, Zhang X, Hall TL, Xu Z “Integrated Histotripsy and Bubble Coalescence Transducer for Thrombolysis“. Ultrasound in Medicine and Biology. 12/2018; 44(12): 2697-709

Lundt JE, Rao A, Fowlkes JB, Cain CA, Lee F Jr., Xu Z “Coalescence of residual histotripsy cavitation nuclei using lowgain regions of the therapy beam during electronic focal steering“. Physics in Medicine and Biology. 2018. 11/2018; 63(22): 225010

H. Alavi Tamaddoni, A. P. Duryea, E. Vlaisavljevich, Z. Xu and T. L. Hall, “Acoustic Methods for Increasing the Cavitation Initiation Pressure Threshold,” in IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, vol. 65, no. 11, pp. 2012-2019, Nov. 2018

Sukovich JR, Cain CA, Pandey AS, Chaudhary N, Camelo-Piragua S, Allen SP, Hall TL, Snell J, Xu Z, Cannata JM, Teofilovic D, Bertolina JA, Kassell N “In vivo histotripsy brain treatment“. Journal of Neurosurgery. 10/2018: 1-8 

Shi A, Xu Z, Lundt J, Tamaddoni HA, Worlikar T, Hall TL. Integrated Histotripsy and Bubble Coalescence Transducer for Rapid Tissue Ablation. IEEE Trans Ultrason Ferroelectr Freq Control. 2018 Jul 23. 

Schuster TG, Wei JT, Hendlin K, Jahnke R, Roberts WW. Histotripsy Treatment of Benign Prostatic Enlargement Using the Vortx R(x) System: Initial Human Safety and Efficacy Outcomes. Urology. 2018 Apr;114:184-187. 

Macoskey, Jonathan J. et al. “Bubble-Induced Color Doppler Feedback Correlates with Histotripsy-Induced Destruction of Structural Components in Liver Tissue.” Ultrasound in Medicine & Biology 44.3 (2018): 602-612,

Macoskey, Jonathan J. et al. “Using the cavitation collapse time to indicate the extent of histotripsy-induced tissue fractionation.” Physics in Medicine & Biology 63.5 (2018)

Macoskey, Jonathan J. et al. “Soft-Tissue Aberration Correction for Histotripsy.” IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control 65.11 (2018)

2017

Gerhardson T, Sukovich JR, Pandey AS, Hall TL, Cain CA, Xu Z. Catheter Hydrophone Aberration Correction for Transcranial Histotripsy Treatment of Intracerebral Hemorrhage: Proof-of-Concept. IEEE Trans Ultrason Ferroelectr Freq Control. 2017 Nov;64(11):1684-1697. 

Gerhardson T, Sukovich JR, Pandey AS, Hall TL, Cain CA, Xu Z. Effect of Frequency and Focal Spacing on Transcranial Histotripsy Clot Liquefaction, Using  Electronic Focal Steering. Ultrasound Med Biol. 2017 Oct;43(10):2302-2317. 

Zhang X, Macoskey JJ, Ives K, Owens GE, Gurm HS, Shi J, Pizzuto M, Cain CA, Xu Z. Non-Invasive Thrombolysis Using Microtripsy in a Porcine Deep Vein Thrombosis Model. Ultrasound Med Biol. 2017 Jul;43(7):1378-1390. 

Lundt, Jonathan E. et al. “Non-invasive, Rapid Ablation of Tissue Volume Using Histotripsy.” Ultrasound in Medicine & Biology 43.12 (2017): 2834-2847.

Allen, Steven et al. “The response of MRI contrast parameters in in vitro tissues and tissue mimicking phantoms to fractionation by histotripsy.” Physics in medicine and biology 62.17(2017):7167.

Macoskey, Jonathan et al. “Real-time acoustic-based feedback for histotripsy therapy.” The Journal of the Acoustical Society of America 141, 3551 (2017).

Sukovich, Jonathan et al. “Transcranial histotripsy acoustic-backscatter localization and aberration correction for volume treatments.” The Journal of the Acoustical Society of America 141, 3490 (2017)

Vlaisavljevich, Eli et al. “Non-Invasive Liver Ablation Using Histotripsy: Preclinical Safety Study in an In Vivo Porcine Model.” Ultrasound in Medicine and Biology 43.6 (2017): 1237-1251

Vlaisavljevich E, Gerhardson T, Hall T, Xu Z “Effects of f-number on the histotripsy intrinsic threshold and cavitation bubble cloud behavior“. Physics in Medicine and Biology. 2017; 62(4): 1269-90

Mancia L , Vlaisavljevich E, Xu Z, Johnsen E “Predicting Tissue Susceptibility to Mechanical Cavitation Damage in Therapeutic Ultrasound“. Ultrasound in Medicine and Biology. 2017; 43(7): 1421-40

2016
 

Miller, Ryan M. et al. “Bubble-Induced Color Doppler Feedback for Histotripsy Tissue Fractionation.” IEEE transactions on ultrasonics, ferroelectrics, and frequency control 63.3 (2016): 408–419.

Sukovich, Jonathan et al. “Histotripsy pulse-reflection for 3D image forming and bubble cloud localization in transcranial applications.” The Journal of the Acoustical Society of America 140, 3083 (2016)

Cain, Charles et al. “Histotripsy: Transcranial applications.”The Journal of the Acoustical Society of America 140, 3030 (2016)

Vlaisavljevich E, Aydin O, Durmaz YY, Lin KW, Fowlkes JB, Xu Z “Effects of Droplet Composition on Nanodroplet-Mediated Histotripsy“. Ultrasound in Medicine and Biology. 2016; 42(4): 931-46

Vlaisavljevich E, Aydin O, Lin KW, Durmaz YY, Fowlkes B, ElSayed ME, Xu Z “The role of positive and negative pressure on cavitation nucleation in nanodroplet-mediated histotripsy“. Physics in Medicine and Biology. 2016; 61(2): 663-82

Zhang X, Owens GE, Cain CA, Gurm HS, Macoskey J, Xu Z “Histotripsy Thrombolysis on Retracted Clots“. Ultrasound in Medicine and Biology. 2016; 42(8): 1903-18

Vlaisavljevich E, Greve J, Cheng X, Ives K, Shi J, Jin L, Arvidson A, Hall T, Welling TH, Owens G, Roberts W, Xu Z “NonInvasive Ultrasound Liver Ablation Using Histotripsy: Chronic Study in an In Vivo Rodent Model“. Ultrasound in Medicine and Biology. 2016; 42(8): 1890-902

Vlaisavljevich E, Maxwell AD, Mancia L, Johnsen E, Cain CA, Xu Z “Visualizing the Histotripsy Process: Bubble CloudCancer Cell Interactions in a Tissue-Mimicking Environment“. Ultrasound in Medicine and Biology. 2016; 42(10): 2466-77

Sukovich J , Xu Z, Kim Y, Cao H, Nguyen TS*, Pandey A, Hall T, Cain C “Targeted Lesion Generation Through the Skull Without Aberration Correction Using Histotripsy“. IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control. 2016; 63(5): 671-682

Vlaisavljevich E, Xu Z, Maxwell A, Mancia L, Zhang X, Lin KW, Duryea A, Sukovich J, Hall T, Johnsen E, Cain C “Effects of Temperature on the Histotripsy Intrinsic Threshold for Cavitation“. IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control. 2016; 63(8): 1064-77

2015

Zhang, Xi et al. “Non-Invasive Thrombolysis Using Histotripsy beyond the ‘Intrinsic’ Threshold (Microtripsy).” IEEE transactions on ultrasonics, ferroelectrics, and frequency control 62.7 (2015): 1342–1355. 

Lin KW, Hall TL, Xu Z, Cain CA “Histotripsy Lesion Formation Using an Ultrasound Imaging Probe Enabled by a LowFrequency Pump Transducer“. Ultrasound in Medicine and Biology. 2015; 41(8): 2148-60

Zhang, Xi et al. “Real-Time Feedback of Histotripsy Thrombolysis Using Bubble-Induced Color Doppler.” Ultrasound in medicine & biology 41.5 (2015): 1386–1401. PMC. Web. 1 June 2018. 

Vlaisavljevich E, Lin K-W, Maxwell AD, Warnez M, Mancia L, Singh R, Putnam AJ, Fowlkes JB, Johnsen E, Cain CA, Xu Z “Effects of Ultrasound Frequency and Tissue Stiffness on the Histotripsy Intrinsic Threshold for Cavitation“. Physics in Medicine and Biology. 2015; 60(6): 2271-92

Khokhlova, VA et al. “Histotripsy Methods in Mechanical Disintegration of Tissue: Toward Clinical Applications.” International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 31.2 (2015): 145–162. 

Devanagondi, Rajiv et al. “Hemodynamic and Hematologic Effects of Histotripsy of Free-Flowing Blood: Implications for US-Mediated Thrombolysis.” Journal of vascular and interventional radiology : JVIR 26.10 (2015): 1559–1565.

Vera A. Khokhlova, J. Brian Fowlkes, William W. Roberts, George R. Schade, Zhen Xu, Tatiana D. Khokhlova, Timothy L. Hall, Adam D. Maxwell, Yak-Nam Wang & Charles A. Cain (2015) Histotripsy methods in mechanical disintegration of tissue: Towards clinical applications, International Journal of Hyperthermia, 31:2, 145-162.

Duryea AP; Roberts WW; Cain CA; Hall TL. “Removal of residual cavitation nuclei to enhance histotripsy erosion of model urinary stones.”  IEEE Trans Ultrason Ferroelectr Freq Control. 62(5):896-904, 2015 May.

Vlaisavljevich E, Xu Z, Arvidson A, Jin L, Roberts W, Cain CA “Effects of Thermal Preconditioning on Tissue Susceptibility to Histotripsy“. Ultrasound in Medicine and Biology. 2015; 41(11): 2938-54

Vlaisavljevich E, Aydin O, Yuksel Durmaz Y, Lin KW, Fowlkes JB, ElSayed M, Xu Z “Effects of Ultrasound Frequency on Nanodroplet-Mediated Histotripsy“. Ultrasound in Medicine and Biology. 2015; 41(8): 2135-47

Zhang X, Jin L, Vlaisavljevich E, Owens GE, Gurm HS, Cain CA, Xu Z “Noninvasive thrombolysis using microtripsy: a parameter study“. IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control. 2015; 62(12): 2092-105